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- Protocol Labs
Protocol Labs portfolio
Protocol Labs has 11 portfolio companies on record at Recent Funding, with 1 investment in the last 12 months.
About this page
It is an investment platform based in San Francisco, US, founded in 2014. Its most recent investment on record is Akave's Seed round in March 2026, alongside No Limit Holdings, Filecoin, Avalanche VC and 1 other. By category, its portfolio leans toward AI infrastructure and compute (3) and Health and bio (2). It has co-invested with CoinFund, Maven 11 Capital and Big Brain Holdings, most often CoinFund (4 rounds).
About Protocol Labs
What Protocol Labs invests in
- AI infrastructure and compute · 3 · 27%
- Health and bio · 2 · 18%
- Developer tools and cloud · 2 · 18%
- Foundation models and research · 2 · 18%
- Crypto x AI · 2 · 18%
- L1s, L2s and rollups · 1 · 9%
- Robotics and hardware · 1 · 9%
- Manufacturing and industrial · 1 · 9%
Protocol Labs recent investments
| Company | Round | Date | Alongside |
|---|---|---|---|
| Seed | No Limit Holdings, Filecoin, Avalanche VC +1 | ||
| Series B+ · $200M | Khosla Ventures, Qatar Investment Authority, Neurotechnology Investors +6 | ||
| round · $2.2M | CMS Holdings, Dieter Fishbein, CV VC +3 | ||
| Series B+ | General Equity Holdings (lead), Riverhorse Investments, Steadview Capital +6 | ||
| Pre-seed · $3.45M | Blockchange Ventures, Lightshift, Blockchain Builders Fund | ||
| Seed · $5.5M | Collab+Currency, Distributed Global (lead), Clem Delangue +7 | ||
| Pre-seed · $3.1M | Graph Paper Capital, Breed, Borderless Capital +2 | ||
| Seed · $8M | Automattic, Amir Shevat, Amjad Masad +11 |
How Protocol Labs invests
Protocol Labs portfolio companies
AAkaveSeed · Mar 2026
SSynchron$200MSeries B+ · Nov 2025
RReppo$2.2Mround · Jan 2025
PPrecision NeuroscienceSeries B+ · Nov 2024
PPrime Intellect$5.5MSeed · Apr 2024
Bbagel.com$3.1MPre-seed · Jan 2024
BBluesky$8MSeed · Jul 2023
GGensyn$43MSeries A · Jun 2023
CCoinList$9.2MSeries A · Apr 2018
GGoldenbacker
CCompute Labsbacker
| Company | Round with Protocol Labs | Total raised | Latest raise |
|---|---|---|---|
L1s, L2s and rollups |
Seed | $10.1M | Mar 2, 2026 Seed |
Health and bio |
Series B+ · $200M | $600M | Jun 29, 2026 Series B+ |
Developer tools and cloud |
round · $2.2M | $2.2M | Jan 17, 2025 round |
Health and bio |
Series B+ | $303M | Sep 24, 2026 Series B+ |
AI infrastructure and compute |
Seed · $5.5M | $135.5M | Jul 20, 2026 Series A |
Foundation models and research |
Pre-seed · $3.1M | $3.1M | Jan 23, 2024 Pre-seed |
Cybersecurity |
Seed · $8M | $123M | Mar 20, 2026 Series B+ |
AI infrastructure and compute |
Series A · $43M | $50.6M | May 4, 2026 Series A |
| Series A · $9.2M | $109.2M | Oct 26, 2021 Series A | |
Fintech |
backer | undisclosed | — |
Crypto x AI |
backer | undisclosed | — |
Most frequent co-investors
CCoinFund4 shared rounds · last Apr 23, 2024
MMaven 11 Capital2 shared rounds · last Jan 23, 2024
BBig Brain Holdings1 shared round · last Mar 2, 2026
NNo Limit Holdings1 shared round · last Mar 2, 2026FFilecoin1 shared round · last Mar 2, 2026
AAvalanche VC1 shared round · last Mar 2, 2026QQatar Investment Authority1 shared round · last Nov 6, 2025
KKhosla Ventures1 shared round · last Nov 6, 2025
IIQT1 shared round · last Nov 6, 2025
KK5 Global1 shared round · last Nov 6, 2025
NNeurotechnology Investors1 shared round · last Nov 6, 2025MMETIS innovative1 shared round · last Nov 6, 2025
Similar investors
SSamsung Catalyst Fund16 companies · 5 deals in 12 mo
MMediaTek6 companies · 3 deals in 12 mo
SSamsung Ventures24 companies · 6 deals in 12 mo
SSamsung Next52 companies · 4 deals in 12 mo
Investors whose portfolios on Recent Funding center on the same category (AI infrastructure and compute).
How this is counted
Firm profile: Fundraising Fox Open Dataset v2026-11, CC BY 4.0. Track-record counts are theirs, not Recent Funding's.
Share is of the 10 rounds on Recent Funding that name Protocol Labs. Rounds with no announced date are left out of the year split, and "round" is a round whose stage is not on file.
Portfolio companies are the companies on Recent Funding with a round that lists Protocol Labs, which is a subset of its real portfolio. API: /api/v1/investors/protocol-labs (get a free API key). More: the most active VC firms and new venture capital funds.