645 Ventures portfolio

645 Ventures has 17 portfolio companies on record at Recent Funding, with 3 investments in the last 12 months.

Website: 645ventures.com.

X: @645ventures.

Type: Venture capital.

Portfolio on Recent Funding: 17.

Deals, last 12 months: 3.

Rounds led: 2 of 9.

Capital in their rounds: $884.7M.

Latest deal: Gimlet Labs · Sep 4, 2026.

About this page

It is a venture capital firm based in New York, US, founded in 2014. It led 2 of the 9 rounds it joined. Its most recent investment on record is Gimlet Labs's $300M Series B+ round in September 2026, alongside Hudson River Trading, Factory, XTX Markets and 14 others. By category, its portfolio leans toward AI agents (5) and Developer tools and cloud (4). It has co-invested with Menlo Ventures, Eclipse and Narya Capital, most often Menlo Ventures (4 rounds).

About 645 Ventures

Firm type: Venture capital.

Headquarters: New York, US.

Founded: 2014.

Stages: Pre-Seed, Seed, Series A.

Sectors: AI & Machine Learning, Consumer, Cybersecurity, Data & Infrastructure, Deep Tech, Developer Tools, Enterprise Software, Fintech, Healthtech, SaaS, Sector Agnostic, Space Tech.

Check size: $1M to $15M.

Leads rounds: Yes.

Portfolio companies: 114.

Exits: 11.

Rounds led: 18.

Funds raised

Fund	Fund #	Size	Announced
6645 Ventures NYC	IV	$194Mvia Shai Goldman's fund list	Dec 1, 2022
6645 Ventures NYC	III	$160Mvia Shai Goldman's fund list	Oct 28, 2020
6645 Ventures NYC	II	$41Mvia Shai Goldman's fund list	Aug 23, 2018

What 645 Ventures invests in

AI agents · 5 · 29%
Developer tools and cloud · 4 · 24%
Data and analytics · 4 · 24%
Cybersecurity · 3 · 18%
Commerce and retail · 3 · 18%
Logistics and mobility · 3 · 18%
AI infrastructure and compute · 2 · 12%
Education · 2 · 12%

645 Ventures recent investments

Company	Round	Date	Alongside
GGimlet Labs	Series B+ · $300M	Sep 4, 2026	Hudson River Trading, Factory, XTX Markets +14
TTrue Anomaly	Series B+	Apr 28, 2026	The Private Shares Fund, Meritech Capital, Eclipse (lead) +10
SSequence	Series A · $20M · lead	Dec 16, 2025	none named
TTrue Anomaly	Series B+ · $260M	Apr 30, 2025	Meritech Capital, Eclipse, Riot Ventures +6
TTrue Anomaly	Series B+ · $100M	Dec 12, 2023	Eclipse, Riot Ventures (lead), Menlo Ventures +5
HHockeyStack	Seed · $2.7M	Nov 16, 2023	Page One Ventures, Soma Capital, General Catalyst (lead) +6
SShop Circle	Series A · $120M · lead	Sep 6, 2023	BlackSheep Ventures, CDP Venture Capital, Primo Capital +4
SShop Circle	Series A · $65M	Jun 29, 2022	Firstminute Capital, NFX (lead), QED Investors (lead) +1

How 645 Ventures invests

Stage	Deals	Capital in rounds
Series A	4 44%	$222M
Series B+	4 44%	$660M
Seed	1 11%	$2.7M

Year	Deals	Capital in rounds
2021	1 11%	$17M
2022	1 11%	$65M
2023	3 33%	$222.7M
2025	2 22%	$280M
2026	2 22%	$300M

645 Ventures portfolio companies

GGimlet Labs$300MSeries B+ · Sep 2026
TTrue AnomalySeries B+ · Apr 2026
SSequence$20MSeries A · Dec 2025
HHockeyStack$2.7MSeed · Nov 2023
SShop Circle$120MSeries A · Sep 2023
BBigEye$17MSeries A · Apr 2021
EEderabacker
SStrellabacker
OOpenHandsbacker
CCube Devbacker
AAttentionbacker
AAptDecobacker
GGoldbellybacker
IInpharmDbacker
VVariancebacker
LLightSprintbacker
GGeneral Computebacker

Company	Round with 645 Ventures	Total raised	Latest raise
GGimlet Labs AI infrastructure and compute	Sep 4, 2026 Series B+ · $300M	$380M	Sep 4, 2026 Series B+
TTrue Anomaly Defense and security	Apr 28, 2026 Series B+	$377M	Apr 28, 2026 Series B+
SSequence Fintech	Dec 16, 2025 Series A · $20M · lead	$20M	Dec 16, 2025 Series A
HHockeyStack Sales and marketing	Nov 16, 2023 Seed · $2.7M	$23.2M	Feb 26, 2025 Series A
SShop Circle AI agents	Sep 6, 2023 Series A · $120M · lead	$185M	Sep 16, 2025 Series B+
BBigEye AI agents	Apr 15, 2021 Series A · $17M	$79M	Oct 27, 2026 Series A
EEdera Robotics and hardware	backer · source	$20M	Feb 25, 2025 Series A
SStrella Data and analytics	backer · source	$14M	Oct 16, 2025 Series A
OOpenHands Developer tools and cloud	backer · source	$23.8M	Nov 18, 2025 Series A
CCube Dev AI agents	backer · source	undisclosed	—
AAttention AI agents	backer	$30M	Jun 23, 2026 Series B+
AAptDeco Commerce and retail	backer	undisclosed	—
GGoldbelly Commerce and retail	backer	undisclosed	—
IInpharmD Health and bio	backer	$6.05M	Dec 12, 2023 Seed
VVariance AI agents	backer	$22M	Apr 10, 2026 Series A
LLightSprint	backer	$6.6M	Oct 14, 2026 Seed
GGeneral Compute AI infrastructure and compute	backer	$115M	Oct 27, 2026 Series A

Most frequent co-investors

Similar investors

Investors whose portfolios on Recent Funding center on the same category (AI agents).

How this is counted

Firm profile: Fundraising Fox Open Dataset v2026-11, CC BY 4.0. Track-record counts are theirs, not Recent Funding's.

Venture funds 645 Ventures raised, from the list of new VC funds compiled by Shai Goldman (Brex). Each size links to the article that states it, or to that list where no article was found. All new funds: new VC funds.

Share is of the 9 rounds on Recent Funding that name 645 Ventures. Rounds with no announced date are left out of the year split, and "round" is a round whose stage is not on file.

Portfolio companies are the companies on Recent Funding with a round that lists 645 Ventures, which is a subset of its real portfolio. API: /api/v1/investors/645-ventures (get a free API key). More: the most active VC firms and new venture capital funds.