Profluent

Profluent is an AI-first protein design company.

Health and bio Education

Latest funding

$106M Series B+ · November 19, 2025

Led by Altimeter Capital · Source: businesswire.com

Funding history ↓

Website: profluent.bio.

X: @ProfluentBio · 4,173 followers.

LinkedIn: profluent-bio.

Categories: Health and bio Education.

Sectors: Artificial Intelligence (AI), Biotechnology, Life Science, Machine Learning.

Stage: Series B+.

Based in: Oakland, United States.

Founded: 2022.

Last round: Nov 19, 2025 · 361 days ago.

Headcount: 11–50 employees.

On Recent Funding since: Sep 29, 2026.

Signals

X account@ProfluentBio · created Sep 10, 2022 (4 years old) · 4,173 followers

Website registeredJul 1, 2022 (4 years old)

About Profluent

Founded in 2022, they develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine.

TIMELINE · MONEY RAISED

Profluent | 1237 days from website to first raise on record

@ProfluentBio·Raised $106M in 1 sourced round·2 signals before the first raise

Money raised, round by round (amounts linked to their source). Pins are dated signals; hover the icons for dates.

Funding rounds

Date	Round	Amount	Lead	Source
Nov 19, 2025	Series B+	$106M	AAltimeter Capital	businesswire.com

Timeline

September 10, 2022
X account created
July 1, 2022
Website created

Founders and team

AM
Ali Madani Co-founder and CEO

@thisismadani · LinkedIn · source: profluent.bio

Investors

Companies like Profluent

AAikiumSeed · Mar 2026
PPhyx44$1.2M · Nov 2022
MMagnet BiomedicineSeries A · Jul 2026
HHyperNorm AI$2.2M Seed · Jun 2026
FFlaskkSeed · May 2026
EEntelo Bio$4M Seed · Apr 2026

Other companies backed by Altimeter Capital

OOnodrim$300M Series A · Nov 2026
AArda$230M · Oct 2026
SSciFin$44M Seed · Sep 2026
HHadrian$1.37B Series B+ · Aug 2026
BBase Power$1B Series B+ · Aug 2026
KK2 Space$500M Series B+ · Jul 2026

Altimeter Capital portfolio →

Sources and API

Every amount links to the page it came from. * Estimated from an accelerator's published standard deal, not a company-specific disclosure. How Recent Funding sources and verifies funding data. The same data as JSON: /api/v1/companies/profluent (get a free API key).