Manifold Bio

Manifold Bio is positioned to be the leading tissue-specific medicines company.

Latest funding

$40M Series A · June 1, 2022

Source: startupintros.com

Total raised: $45M across 2 sourced rounds

All 2 rounds ↓

Website: manifold.bio.

X: @ManifoldBio · 2,209 followers.

LinkedIn: manifold-bio.

Categories: Health and bio Real estate and construction Logistics and mobility.

Stage: Series A.

Based in: Boston, United States.

Total raised: $45M in 2 sourced rounds.

Last round: Jun 1, 2022 · 1,628 days ago.

On Recent Funding since: Sep 30, 2026.

Signals

X account@ManifoldBio · created Feb 13, 2019 (7 years old) · 2,209 followers

Website registeredSep 22, 2018 (8 years old)

About Manifold Bio

We’ve built the first high-throughput in vivo (HTV) discovery engine - combining massively multiplexed in vivo screening and AI-powered design to create targeted biologics. Our engine sculpts pharmacokinetics, biodistribution, and other key properties of biologics directly in living systems, solving previously intractable challenges for tissue-specific delivery.

TIMELINE · MONEY RAISED

Manifold Bio | 710 days from website to first raise on record

@ManifoldBio·Raised $45M in 2 sourced rounds·2 signals before the first raise

Money raised, round by round (amounts linked to their source). Pins are dated signals; hover the icons for dates.

Funding rounds

Date	Round	Amount	Lead	Source
Jun 1, 2022	Series A	$40M	—	startupintros.com
Sep 1, 2020	Seed	$5M	—	startupintros.com

Timeline

February 13, 2019
X account created
September 22, 2018
Website created

Founders and team

GC
George Church Founder

source: manifold.bio
GK
Gleb Kuznetsov Founder

source: manifold.bio
PO
Pierce Ogden Founder

source: manifold.bio
SL
Shane Lofgren Founder

source: manifold.bio

Companies like Manifold Bio

LLatus Bio$97M Series A · May 2026
NnChroma Bio$75M · Dec 2024
RReCode TherapeuticsSeries B+ · Oct 2023
MMindpeak$15.3M Series A · Oct 2024
AAtrandi Biosciences$25M Series A · Feb 2025
BBiolincoPre Seed · Mar 2026

Sources and API

Every amount links to the page it came from. * Estimated from an accelerator's published standard deal, not a company-specific disclosure. How Recent Funding sources and verifies funding data. The same data as JSON: /api/v1/companies/manifold-bio (get a free API key).