City Therapeutics

City Therapeutics is a clinical-stage biotechnology company that develops RNAi therapeutics.

Health and bio Logistics and mobility

Latest funding

$99.5M Series B+ · June 8, 2026

Led by Sofinnova Partners · Source: fundraisingfox.com

Latest round on record: Series B+, August 2026, amount undisclosed.

Total raised: $234.5M across 2 sourced rounds

All 3 rounds ↓

Website: citytx.com.

X: @CityTx_ · 180 followers.

LinkedIn: city-therapeutics.

Categories: Health and bio Logistics and mobility.

Sectors: Biopharma, Life Science, Therapeutics.

Stage: Series B+.

Based in: Cambridge, United States.

Founded: 2023.

Total raised: $234.5M in 2 sourced rounds.

Last round: Aug 8, 2026 · 99 days ago.

Headcount: 11–50 employees.

On Recent Funding since: Sep 29, 2026.

Signals

X account@CityTx_ · created Sep 23, 2024 (2 years old) · 180 followers

Website registeredFeb 18, 2006 (20 years old)

About City Therapeutics

It engineers RNAi trigger molecules and pairs them with tissue-targeting ligands for precise delivery. The company aims to deliver benefits for patients in need and builds a pipeline in diseases where RNAi offers an advantage.

TIMELINE · MONEY RAISED

City Therapeutics | 15 days from X account to first raise on record

@CityTx_·Raised $235M in 2 sourced rounds·1 signal before the first raise

Money raised, round by round (amounts linked to their source). Pins are dated signals; hover the icons for dates.

Funding rounds

Date	Round	Amount	Lead	Source
Aug 8, 2026	Series B+	undisclosed	—	fundraisingfox.com
Jun 8, 2026	Series B+	$99.5M	SSofinnova Partners	fundraisingfox.com
Oct 8, 2024	Series A	$135M	AARCH Venture Partners	Business Wire

Timeline

September 23, 2024
X account created
February 18, 2006
Website created

Founders and team

AN
Ari Nowacek Founder
JM
John Maraganore Founder

@JMaraganore · LinkedIn
RN
Robert Nelsen Founder

@rtnarch
ST
Sebastian Trousil Founder

LinkedIn
AO
Andrew Orth Chief Executive Officer
KR
Keith Regnante Chief Financial Officer
MD
Mary DeLena Chief Legal Officer and Secretary

Investors

Companies like City Therapeutics

NNoema PharmaSeries B+ · Nov 2025
SStorm Therapeutics$56M Series B+ · Apr 2026
CCellCentric$220M Series B+ · May 2026
FFoRx Therapeutics$50M Series A · Dec 2025
RReCode TherapeuticsSeries B+ · Oct 2023
IImmunis BiomedicalSeries A · Aug 2022

Other companies backed by Sofinnova Partners

AAlethio Therapeutics$90M Series A · Nov 2026
TT-Therapeutics$133M Series B+ · Nov 2026
DDMC Biotechnologies$18M Series B+ · Oct 2026
SStar Therapeutics$200M Series B+ · Oct 2026
IIMIO$12M Seed · Oct 2026
CClaris Bio$118M Series B+ · Jul 2026

Sofinnova Partners portfolio →

Sources and API

Every amount links to the page it came from. * Estimated from an accelerator's published standard deal, not a company-specific disclosure. How Recent Funding sources and verifies funding data. The same data as JSON: /api/v1/companies/city-therapeutics (get a free API key).